Description:
Clopidogrel is a blood thinner which prevents formation of harmful blood clots. It reduces the risk of having another heart attack, stroke, or blood clots in stents. It can be used alone or in combination with other medicines. This medicine should be taken strictly as advised by the doctor and should not be stopped abruptly. It can increase the risk of bleeding, so be careful while shaving, cutting nails, using sharp objects, or engaging in contact sports (e.g. football, wrestling). Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool (black or tarry). This medicine may need to be stopped temporarily before a planned surgery or dental treatment. Unlike aspirin, it does not cause any gastritis (stomach pain/burning and nausea).
Uses / Indications:
Prevention of heart attack and stroke Heart attack Peripheral vascular disease
Interactions / Warnings:
warnings Alcohol CAUTION It is unsafe to consume alcohol with Clopidogrel. warnings Pregnancy PROBABLY SAFE Clopidogrel is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor. warnings Lactation Clopidogrel is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. warnings Driving SAFE Clopidogrel does not usually affect your ability to drive. warnings Kidney There is limited information aVialable on the use of Clopidogrel in patients with kidney disease. Please consult your doctor. warnings Liver There is limited information aVialable on the use of Clopidogrel in patients with liver disease. Please consult your doctor.
Side Effects:
Increased bleeding tendency
How to use:
To be used as directed by physician
How it works:
Clopidogrel bisulfate is a prodrug that is metabolized to the active form, (thiol derivative) that inhibits platelet aggregation by selectively and irreversibly binding to the adenosine diphosphate (ADP) P2Y12 receptor on platelets. This binding prevents activation of the ADP-mediated glycoprotein GPIIb/IIIa complex, which is necessary for platelet aggregation. This action is irreversible for the remainder of the platelet lifespan (7 to 10 days).